SRA1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Steroid receptor RNA activator 1 also known as steroid receptor RNA activator protein (SRAP) is a protein that in humans is encoded by the SRA1 gene.[1][2] The mRNA transcribed from the SRA1 gene is a component of the ribonucleoprotein complex containing NCOA1. This functional RNA also encodes a protein.[3]
Function
This gene is involved in transcriptional coactivation by steroid receptor. There is currently data suggesting this gene encodes both a non-coding RNA that functions as part of a ribonucleoprotein complex and a protein coding mRNA. Increased expression of both the transcript and the protein is associated with cancer.[2]
Interactions
SRA1 has been shown to interact with:
The SRAP has been shown to interact with its SRA RNA counterpart indirectly with the functional sub-structure STR7 of SRA RNA.[6] Originally proposed to be RRM containing, SRAP has been demonstrated to have a helix bundle at its C-terminal end while N-terminal to this domain appears unstructured.[7]
References
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Further reading
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External links
- SRA1 human gene location in the UCSC Genome Browser.
- SRA1 human gene details in the UCSC Genome Browser.
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