ASB1

Ankyrin repeat and SOCS box containing 1
Identifiers
Symbols	ASB1 ; ASB-1
External IDs	OMIM: 605758 MGI: 1929735 HomoloGene: 9390 GeneCards: ASB1 Gene
Gene ontology Molecular function • molecular_function Cellular component • intracellular Biological process • protein ubiquitination • male genitalia development • intracellular signal transduction • negative regulation of cytokine biosynthetic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51665	65247
Ensembl	ENSG00000065802	ENSMUSG00000026311
UniProt	Q9Y576	Q9WV74
RefSeq (mRNA)	NM_001040445	NM_001039126
RefSeq (protein)	NP_001035535	NP_001034215
Location (UCSC)	Chr 2: 238.43 – 238.45 Mb	Chr 1: 91.54 – 91.56 Mb
PubMed search	[1]	[2]

Ankyrin repeat and SOCS box protein 1 is a protein that is in humans, encoded by the ASB1 gene.

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.