Anserine

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Anserine
200px
Names
IUPAC name
(2S)-2-[(3-Amino-1-oxopropyl)amino]-3-(3-methyl-4-imidazolyl)propanoic acid
Other names
beta-Alanyl-N(pi)-methyl-L-histidine
Identifiers
584-85-0 YesY
ChEBI CHEBI:18323 YesY
ChEMBL ChEMBL448301 YesY
ChemSpider 100482 YesY
Jmol 3D model Interactive image
KEGG C01262 YesY
PubChem 112072
  • InChI=1S/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1 YesY
    Key: MYYIAHXIVFADCU-QMMMGPOBSA-N YesY
  • InChI=1/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1
    Key: MYYIAHXIVFADCU-QMMMGPOBBJ
  • O=C(O)[C@@H](NC(=O)CCN)Cc1cncn1C
Properties
C10H16N4O3
Molar mass 240.25904
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Anserine (beta-alanyl-N-methylhistidine) is a dipeptide containing β-alanine and histidine,[1] which can be found in the skeletal muscle and brain of mammals[2] and birds.

The pKa of the imidazole ring of histidine, when contained in anserine, is 7.04, making it an effective buffer at physiologic pH.[3]

See also

References

  1. Biochemistry, Garrett & Grisham, pg. 46
  2. Quantitative studies of carnosine and anserine in mammalian muscle. 1938 (pdf)
  3. Biochemistry, Garrett & Grisham


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