CRADD
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Death domain-containing protein CRADD is a protein that in humans is encoded by the CRADD gene.[1][2][3]
Function
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.[3]
Interactions
CRADD has been shown to interact with RIPK1[1][2] and Caspase 2.[1][4][5]
References
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<references />, or <references group="..." />Further reading
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This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it. |
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