CRMP1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.[1]
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.[1]
CRMP1 mediates reelin signaling in cortical neuronal migration.[2] Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory.[3]
CRMP1 gene overlaps with another gene called EVC.[4]
Interactions
CRMP1 has been shown to interact with DPYSL2.[5]
References
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Further reading
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