DACH1

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Dachshund homolog 1 (Drosophila), also known as DACH1, is a protein which in humans is encoded by the DACH1 gene.[1][2][3]

Function

This gene is similar to the D. melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a member of the Ski gene family and is thought to be involved in eye development. Four alternatively spliced transcripts encoding different isoforms have been described for this gene.[3]

Interactions

DACH1 has been shown to interact with UBE2I,[4][5] Smad4 and NCoR.[6]

References

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Further reading

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