DSN1
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| DSN1 homolog, MIS12 kinetochore complex component | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | DSN1 ; C20orf172; KNL3; MIS13; dJ469A13.2; hKNL-3 | ||||||||||||
| External IDs | OMIM: 609175 MGI: 1914184 HomoloGene: 49806 GeneCards: DSN1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| File:PBB GE DSN1 219512 at tn.png | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 79980 | 66934 | |||||||||||
| Ensembl | ENSG00000149636 | ENSMUSG00000027635 | |||||||||||
| UniProt | Q9H410 | Q9CYC5 | |||||||||||
| RefSeq (mRNA) | NM_001145315 | NM_025853 | |||||||||||
| RefSeq (protein) | NP_001138787 | NP_080129 | |||||||||||
| Location (UCSC) | Chr 20: 36.75 – 36.77 Mb |
Chr 2: 157 – 157.01 Mb |
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| PubMed search | [1] | [2] | |||||||||||
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae), also known as DSN1 or MIS13, is a protein which in humans encoded by the DSN1 gene.[1][2]
Function
DSN1 along with MIS12, DC8, PMF1, CBX5, ZWINT is a component of the kinetochore-associated multiprotein complex which is required for correct chromosome alignment during the metaphase of cell mitosis.[2][3]
Interactions
DSN1 has been shown to interact with NSL1[4] and MIS12.[2][5]
References
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Further reading
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