Wakefulness-promoting agent

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A wakefulness-promoting agent, or eugeroic, is a type of drug which specifically improves wakefulness and alertness.[1][2] They are used mainly in the treatment of sleeping disorders, excessive daytime sleepiness and narcolepsy.[1][2] They are also used merely to counteract fatigue and lethargy and to enhance motivation and productivity.[medical citation needed] Wakefulness-promoting agents are addictive,[1][2] although not necessarily to the same extent as other addictive stimulants.

The prototypical eugeroic is modafinil, and other drugs include adrafinil and armodafinil. Modafinil and armodafinil are dopamine reuptake inhibitors.[1][2]

The functional opposites of wakefulness-promoting agents are hypnotics, such as H1 antihistamines that cross the blood–brain barrier and suvorexant, an orexin antagonist.

Examples

Wakefulness Reducing Agent

The only functional opposite of wakefulness enhancing agents.

See also

References

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  2. ↑ 2.0 2.1 2.2 2.3 Lua error in package.lua at line 80: module 'strict' not found.

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