Evodiamine

Evodiamine

Skeletal formula
Space-filling model
Systematic (IUPAC) name
21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
Identifiers
CAS Number	518-17-2 Y
ATC code	none
PubChem	CID: 151289
ChemSpider	133343 Y
ChEMBL	CHEMBL486598 N
Chemical data
Formula	C19H17N3O
Molecular mass	303.36 g/mol
SMILES O=C4N3CCc2c(nc1ccccc12)C3N(c5ccccc45)C
InChI InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3 Y Key:TXDUTHBFYKGSAH-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Evodiamine is a chemical extracted from the Tetradium genus of plants, which has been shown to reduce fat uptake in mouse studies. It is suspected that its mechanism of action is similar to that of capsaicin. As such, it has been included in some dietary supplements. Neither its fat-burning effects in humans nor any potential side effects have been empirically established.

Evodiamine acts primarily as a thermogenic and stimulant.

Evodiamine may also act in a manner comparable to tianeptine by increasing the number of serotonin transporters available in the brain, enhancing the reuptake of serotonin.