Flestolol

Flestolol

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Names
IUPAC name 3-{[1-(Carbamoylamino)-2-methyl-2-propanyl]amino}-2-hydroxypropyl 2-fluorobenzoate
Identifiers
CAS Number	87721-62-8
ChemSpider	50465
Jmol 3D model	Interactive image
PubChem	55885
InChI InChI=1S/C15H22FN3O4/c1-15(2,9-18-14(17)22)19-7-10(20)8-23-13(21)11-5-3-4-6-12(11)16/h3-6,10,19-20H,7-9H2,1-2H3,(H3,17,18,22) Key: ZPLOQFLCMVIWRY-UHFFFAOYSA-N
SMILES CC(C)(CNC(=O)N)NCC(COC(=O)C1=CC=CC=C1F)O
Properties
Chemical formula	C15H22FN3O4
Molar mass	327.36 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Flestolol is a short-acting beta adrenergic receptor antagonist.

Synthesis

File:Flestolol synthesis.svg

Flestolol synthesis:

Acylation of glycidol (2) with the acid chloride 1 produces the ester 3. Reaction of that intermediate with amine 4, obtained by reaction of 1,1-dimethylethylenediamine with urea, gives flestolol (5).