GAB1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene.[1]
Function
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. The encoded protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.[2] The expression of GAB1 was also implicated in the biology of B cell malignancies, and is regulated by non-coding RNA (miRNA) termed miR-150.[3]
Interactions
GAB1 has been shown to interact with:
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References
- ↑ 1.0 1.1 1.2 1.3 Lua error in package.lua at line 80: module 'strict' not found.
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- ↑ 9.0 9.1 Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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Further reading
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