Hypervitaminosis E
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| Hypervitaminosis E | |
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Tocopherol, or vitamin E.
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| Patient UK | Hypervitaminosis E |
Hypervitaminosis E is a state of vitamin E toxicity. Since vitamin E can act as an anticoagulant and may increase the risk of bleeding problems, many agencies have set a tolerable upper intake levels (UL) for vitamin E at 1,000 mg (1,500 IU) per day.[1] This UL was established due to an increased incidence of hemorrhaging with higher doses of supplemental vitamin E. Doses of vitamin E above the UL can also magnify the antiplatelet effects of certain drugs such as anti-coagulant medications and aspirin, which can cause life-threatening symptoms in ill patients. Hypervitaminosis E may also counteract vitamin K, leading to a vitamin K deficiency.
Signs and symptoms
- Blotchy skin
- Increased bleeding
- Increased blood level of triglycerides
- Decreased production of thyroid hormones
- Decreased activity of vitamin K
- Increased bleeding from aspirin or anti-coagulant medications
See also
References
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