MDGA2

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MAM domain containing glycosylphosphatidylinositol anchor 2
Identifiers
Symbol MDGA2
Alt. symbols MAMDC1
Entrez 161357
HUGO 19835
OMIM 611128
RefSeq NM_182830
Other data
Locus Chr. 14 q21.2

MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is a human gene. It has previously been called MAMDC1.[1] MDGA2 is located on chromosome 14.

The gene has a homologue in rat and mouse, Mdga2,[2] and investigations in rats have found that the gene is expressed in the central and peripheral nervous system in a subpopulation of neurons, e.g., in the basilar pons and cerebral cortex.[3]

There are several variants in the human gene,[4] and a genome-wide association study has pointed to that single-nucleotide polymorphisms in MDGA2 is associated with neuroticism.[5]

References

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