n-Butylamine
| Skeletal formula of n-butylamine | |
| Ball-and-stick model of the N-butylamine molecule | |
| Names | |
|---|---|
| IUPAC name
Butan-1-amine[1]
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Other names
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| Identifiers | |
109-73-9  |
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| Abbreviations | NBA |
| 605269 | |
| ChEBI | CHEBI:43799  |
| ChEMBL | ChEMBL13968 |
| ChemSpider | 7716 |
| DrugBank | DB03659 |
| EC Number | 203-699-2 |
| 1784 | |
| Jmol 3D model | Interactive image |
| MeSH | n-butylamine |
| PubChem | 8007 |
| RTECS number | EO29750002 |
| UNII | N2QV60B4WR |
| UN number | 1125 |
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| Properties | |
| C4H11N | |
| Molar mass | 73.14 g·mol−1 |
| Appearance | Colorless liquid |
| Odor | fishy, ammoniacal |
| Density | 740 mg mL−1 |
| Melting point | −49 °C; −56 °F; 224 K |
| Boiling point | 77 to 79 °C; 170 to 174 °F; 350 to 352 K |
| Miscible | |
| log P | 1.056 |
| Vapor pressure | 9.1 kPa (at 20 °C) |
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Henry's law
constant (kH) |
570 μmol Pa−1 kg−1 |
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Refractive index (nD)
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1.401 |
| Viscosity | 500 µPa s (at 20 °C) |
| Thermochemistry | |
| 188 J K−1 mol−1 | |
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Std enthalpy of
formation (ΔfH |
−128.9–−126.5 kJ mol−1 |
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Std enthalpy of
combustion (ΔcH |
−3.0196–−3.0174 MJ mol−1 |
| Vapor pressure | {{{value}}} |
| Related compounds | |
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Related alkanamines
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Related compounds
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2-Methyl-2-nitrosopropane |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is ?) |
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| Infobox references | |
n-Butylamine is an organic compound (specifically, an amine) with the formula CH3CH2CH2CH2NH2. This colourless liquid is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine and isobutylamine. At standard temperature and pressure, n-butylamine is a liquid having the fishy, ammonia-like odor common to amines. The liquid acquires a yellow color upon storage in air. It is soluble in all organic solvents.
Like other simple, aliphatic amines, n-butylamine is a weak base, with a pKa, in its protonated form, of 10.59.[2]
Uses
This compound is used as an ingredient in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifiers. It is also a precursor for the manufacture of N,N'-dibutylthiourea, a rubber vulcanization accelerator, and n-butylbenzenesulfonamide, a plasticizer of nylon.
Safety
The LD50 to rats through the oral exposure route is 366 mg/kg.[3]
In regards to occupational exposures to n-Butylamine, the Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits at a ceiling of 5 ppm (15 mg/m3) for dermal exposure.[4]
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ H. K. Hall (1957) J. Am. Chem. Soc. 79 5441.
- ↑ n-Butylamine MSDS
- ↑ CDC - NIOSH Pocket Guide to Chemical Hazards
