NDEL1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Nuclear distribution protein nudE-like 1 is a protein that in humans is encoded by the NDEL1 gene.[1][2][3]
This gene encodes a thiol-activated oligopeptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[3]
Interactions
NDEL1 has been shown to interact with Cyclin-dependent kinase 5,[1] YWHAE,[4] PAFAH1B1[1][4] and DISC1.[5][6]
References
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