Pexelizumab
From Infogalactic: the planetary knowledge core
Monoclonal antibody | |
---|---|
Type | Single-chain variable fragment |
Source | Humanized (from mouse) |
Target | Complement component 5 |
Clinical data | |
Legal status |
|
Identifiers | |
ATC code | none |
UNII | CHZ6OLQ3UU ![]() |
(verify) |
Pexelizumab is a drug designed to reduce side effects of coronary artery bypass grafting[1] and angioplasty,[2][3] among other types of cardiac surgery. It is a single chain variable fragment of a monoclonal antibody targeted against component 5 of the complement system.[4]
Current Status
Alexion, the developer of pexelizumab stopped development due to disappointing phase 3 results indicating the heart-attack drug is no better than placebo.[5]
References
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- ↑ ClinicalTrials.gov: Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass
- ↑ ClinicalTrials.gov: Pexelizumab in Conjunction With Angioplasty in Acute Myocardial Infarction
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ [1] Analysis: Alexion's pexelizumab fails
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