Policresulen

Policresulen

File:Policresulen.png
File:Policresulen ball-and-stick.png
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	topical
Identifiers
CAS Number	101418-00-2 N
ATC code	D08AE02 (WHO) G01AX03 QG51AD02 (WHO)
PubChem	CID: 3050404
Chemical data
Formula	(C9H8O4S)n
Molecular mass	variable
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Policresulen is a topical haemostatic and antiseptic. It is indicated for common anal disorders, such as hemorrhoids, and for gynecological infections. In some countries it is marketed under the trade name Albothyl or Polilen (Taiwan) or Faktu (combination with Cinchocaine).

Medical Uses

Policresulen is often used for gynecological infections. In some countries, it is also used to treat canker sore. Although there is an immense pain followed by the application on canker sore, it is considered as a very effective treatment.

Mechanism of Action

As one can see from the chain of Policresulen, the molecule is negatively charged, making it acidic. In fact, its pKa is less than 0, yet it considered weak acid. The mechanism of action is that normal cells are negatively charged, therefore repelling each other. However, wounded part is positively charged, causing the Policresulen to be attracted. Policresulen basically makes a slight chemical burn on the wounded area, thus killing the bacteria and making it antiseptic.