SKBR3
From Infogalactic: the planetary knowledge core
SkBr3 is a cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970. It was derived from a pleural effusion due to an adenocarcinoma originating in the breast of a 43-year-old, caucasian female. The cell line over-expresses the HER2 gene product. [1]
The SkBr3 line is synonymous(derived from the same patient) with the AU565 cell line.[2]
The SkBr3 cell line has been used in studies seeking to overcome Herceptin resistance to HER2-overexpressing breast cancer.[3]
The cells are considered biosafety level 1.[1]
