Tanaproget

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
Tanaproget
Tanaproget.svg
Systematic (IUPAC) name
5-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Clinical data
Legal status
  • Investigational
Identifiers
CAS Number 304853-42-7
ATC code none
PubChem CID: 4369524
DrugBank DB04787
ChemSpider 3572060
Chemical data
Formula C16H15N3OS
Molecular mass 297.375 g/mol
  • CC1(C2=C(C=CC(=C2)C3=CC=C(N3C)C#N)NC(=S)O1)C
  • InChI=1S/C16H15N3OS/c1-16(2)12-8-10(4-6-13(12)18-15(21)20-16)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,21)
  • Key:PYVFWTPEBMRKSR-UHFFFAOYSA-N

Tanaproget (INN; developmental code names NSP-989, WAY-166989) is an investigational non-steroidal progestin.[1] It is a high affinity, high efficacy, and very selective agonist of the progesterone receptor (PR).[1] Due to its much more selective binding profile relative to most conventional, steroidal progestins, tanaproget may prove to produce fewer side effects in comparison.[1] As of December 2010,[2] it is in phase II clinical trials in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals.[3][4]

An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography.[5]

See also

References

<templatestyles src="Reflist/styles.css" />

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />



<templatestyles src="Asbox/styles.css"></templatestyles>

Stub icon

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.
  1. ↑ 1.0 1.1 1.2 Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Tanaproget
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
Retrieved from "https://infogalactic.com/w/index.php?title=Tanaproget&oldid=713249312"