Template:PBB/2206

Membrane-spanning 4-domains, subfamily A, member 2
Identifiers
Symbols	MS4A2 ; APY; ATOPY; FCER1B; FCERI; IGEL; IGER; IGHER; MS4A1
External IDs	OMIM: 147138 MGI: 95495 HomoloGene: 112 GeneCards: MS4A2 Gene
Gene ontology Molecular function • IgE receptor activity • IgE binding • protein kinase binding • SH2 domain binding • phosphoprotein binding Cellular component • endosome • plasma membrane • integral component of plasma membrane • external side of plasma membrane • Fc-epsilon receptor I complex • membrane raft Biological process • inflammatory response • immune response • activation of phospholipase C activity • protein kinase C-activating G-protein coupled receptor signaling pathway • Fc-epsilon receptor signaling pathway • positive regulation of mast cell degranulation • innate immune response • cytokine secretion • regulation of release of sequestered calcium ion into cytosol Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE MS4A2 207497 s at tn.png
File:PBB GE MS4A2 207496 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2206	14126
Ensembl	ENSG00000149534	ENSMUSG00000024680
UniProt	Q01362	P20490
RefSeq (mRNA)	NM_000139	NM_001276328
RefSeq (protein)	NP_000130	NP_001263257
Location (UCSC)	Chr 11: 60.09 – 60.1 Mb	Chr 19: 11.62 – 11.62 Mb
PubMed search	[1]	[2]