TUB (gene)

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Tubby protein homolog is a protein that in humans is encoded by the TUB gene.[1][2]

This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.[2]

Interactions

TUB (gene) has been shown to interact with PLCG1.[3]

References

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Further reading

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