4′-Fluorococaine

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4′-Fluorococaine
4-fluorococaine.png
Systematic (IUPAC) name
methyl (1R,2R,3S,5S)-3-(4-fluorobenzoyloxy)-8-methyl-8-azabicyclo[3.2.1] octane-2-carboxylate
Identifiers
CAS Number 134507-62-3
PubChem CID: 126112
ChemSpider 112124 YesY
Chemical data
Formula C17H20FNO4
Molecular mass 321.343 g/mol
  • CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=C(C=C3)F)C(=O)OC
  • InChI=1S/C17H20FNO4/c1-19-12-7-8-13(19)15(17(21)22-2)14(9-12)23-16(20)10-3-5-11(18)6-4-10/h3-6,12-15H,7-9H2,1-2H3/t12-,13-,14-,15+/m0/s1 YesY
  • Key:JRPRINGETIYVSV-ZQDZILKHSA-N YesY
  (verify)

4′-Fluorococaine is a tropane derivative drug which is a synthetic analogue of cocaine. Unlike related compounds such as the corresponding 4′-fluorophenyltropane derivative CFT and the 2′-hydroxy analogue salicylmethylecgonine, 4′-fluorococaine has only around the same potency as cocaine as an inhibitor of dopamine reuptake, but conversely it is a much stronger serotonin reuptake inhibitor than cocaine, resulting in a significantly altered pharmacological profile in animal studies.[1]

See also

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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