CDH12
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Cadherin-12 is a protein that in humans is encoded by the CDH12 gene.[1][2]
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of an HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.[2]
References
Further reading
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External links
- CDH12 human gene location in the UCSC Genome Browser.
- CDH12 human gene details in the UCSC Genome Browser.
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