O-1871

O-1871

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Systematic (IUPAC) name
2-(3,3-dimethylcyclohexyl)-5-(2-methyloctan-2-yl)benzene-1,3-diol
Clinical data
Legal status	Banned as cyclohexylphenol derivative (US, UK)
Identifiers
CAS Number	620964-96-7
ATC code	none
PubChem	CID: 10405368
ChemSpider	8580806
Chemical data
Formula	C23H38O2
Molecular mass	346.55 g/mol
SMILES CC(C1)(C)CCCC1C2=C(O)C=C(C(C)(C)CCCCCC)C=C2O
InChI InChI=1S/C23H38O2/c1-6-7-8-9-13-23(4,5)18-14-19(24)21(20(25)15-18)17-11-10-12-22(2,3)16-17/h14-15,17,24-25H,6-13,16H2,1-5H3 Key:WBSPBIRKSHKQQD-UHFFFAOYSA-N

O-1871 is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a CB₁ receptor affinity of 2.0nM and a CB₂ receptor affinity of 0.3nM. Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in most jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative, which are not cyclohexylphenol derivatives.

See also

• CP 55,940
• Cannabidiol
• Cannabicyclohexanol