Resiquimod

Resiquimod
	200px
Systematic (IUPAC) name
	1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
Clinical data
Legal status	Investigational;
Routes of; administration	Topical
Identifiers
CAS Number	144875-48-9
ATC code	none
PubChem	CID: 159603
IUPHAR/BPS	5051
ChemSpider	140330
UNII	V3DMU7PVXF
ChEMBL	CHEMBL383322
Chemical data
Formula	C17H22N4O2
Molecular mass	314.382 g/mol
	SMILES CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N ;
	InChI InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19) ; Key:BXNMTOQRYBFHNZ-UHFFFAOYSA-N ;
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Resiquimod (R-848) is a drug that acts as an immune response modifier, and has antiviral and antitumour activity. It is used as a topical gel^[1] in the treatment of skin lesions^[2] such as those caused by the herpes simplex virus^[3]^[4] and cutaneous T cell lymphoma,^[5] and as an adjuvant to increase the effectiveness of vaccines.^[6] It has several mechanisms of action, being both an agonist for toll-like receptor 7 and 8,^[7] and an upregulator of the opioid growth factor receptor.^[8]

References

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