SNF1LK

Salt-inducible kinase 1
Identifiers
Symbols	SIK1 ; EIEE30; MSK; SIK; SNF1LK
External IDs	OMIM: 605705 MGI: 104754 HomoloGene: 136094 ChEMBL: 6082 GeneCards: SIK1 Gene
EC number	2.7.11.1
Gene ontology Molecular function • magnesium ion binding • protein serine/threonine kinase activity • protein binding • ATP binding • cAMP response element binding protein binding • protein kinase binding • 14-3-3 protein binding Cellular component • nucleus • cytoplasm Biological process • regulation of sodium ion transport • protein phosphorylation • cell cycle • regulation of mitotic cell cycle • regulation of myotube differentiation • negative regulation of triglyceride biosynthetic process • negative regulation of CREB transcription factor activity • intracellular signal transduction • entrainment of circadian clock by photoperiod • regulation of cell differentiation • negative regulation of gluconeogenesis • protein autophosphorylation • rhythmic process • cardiac muscle cell differentiation • positive regulation of anoikis Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE SNF1LK 208078 s at tn.png
File:PBB GE SNF1LK gnf1h01351 x at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	150094	17691
Ensembl	ENSG00000142178	ENSMUSG00000024042
UniProt	P57059	Q60670
RefSeq (mRNA)	NM_173354	NM_010831
RefSeq (protein)	NP_775490	NP_034961
Location (UCSC)	Chr 21: 43.41 – 43.43 Mb	Chr 17: 31.84 – 31.86 Mb
PubMed search	[1]	[2]

Serine/threonine-protein kinase SIK1 is an enzyme that in humans is encoded by the SIK1 gene.