CAMP responsive element modulator
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). cAMP-responsive element modulator is a protein that in humans is encoded by the CREM gene.[1][2][3]
Function
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.[3]
Interactions
CAMP responsive element modulator has been shown to interact with FHL5.[4][5]
References
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External links
- CREM protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it. |
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