Ezlopitant

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Ezlopitant
Ezlopitant.png
Systematic (IUPAC) name
(2S,3S)-2-benzhydryl-N-[(5-isopropyl-2-methoxy-phenyl)methyl]quinuclidin-3-amine
Clinical data
Legal status
  • Uncontrolled
Routes of
administration		 Oral
Pharmacokinetic data
Excretion Urine (32%), Feces (51%)
Identifiers
CAS Number 147116-64-1
ATC code none
PubChem CID: 188927
IUPHAR/BPS 5751
ChemSpider 164166
UNII 3L098A8MPY YesY
ChEMBL CHEMBL515966
Chemical data
Formula C31H38N2O
Molecular mass 454.65 g/mol

Ezlopitant (CJ-11,974) is an NK1 receptor antagonist.[1][2][3] It has antiemetic and antinociceptive effects.[4][5] Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome but it appears to have been discontinued.[1]

See also

References

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