Furethidine

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Furethidine
Furethidine.svg
Systematic (IUPAC) name
ethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
Clinical data
Legal status
Identifiers
CAS Number 2385-81-1
ATC code none
PubChem CID: 61306
DrugBank DB01464 YesY
ChemSpider 55245 YesY
UNII 6U9XA4JOD4 YesY
ChEMBL CHEMBL2105078
Synonyms ethyl 4-phenyl-1-(2-tetrahydrofurfuryloxyethyl)piperidine-4-carboxylate
Chemical data
Formula C21H31NO4
Molecular mass 361.48 g/mol
  • O=C(OCC)C3(c1ccccc1)CCN(CCOCC2OCCC2)CC3
  • InChI=1S/C21H31NO4/c1-2-25-20(23)21(18-7-4-3-5-8-18)10-12-22(13-11-21)14-16-24-17-19-9-6-15-26-19/h3-5,7-8,19H,2,6,9-17H2,1H3 YesY
  • Key:NNCOZXNZFLUYGG-UHFFFAOYSA-N YesY
  (verify)

Furethidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine).[1]

Furethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.[2] In the United States it is a Schedule I Narcotic controlled substance with the ACSCN of 9626.[3]

References

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  1. ↑ Maul C, Buschmann H, Sundermann B. Opioids: 3.3 Synthetic Opioids. Analgesics 2005; 159-169. ISBN 978-3-527-30403-5
  2. ↑ Cahal DA, Dare JG, Keith D. A Sequential Trial of Analgesics in Labour. International Journal of Obstetrics and Gynaecology 1961; 68(1): 88–93.
  3. ↑ http://www.deadiversion.usdoj.gov/schedules/orangebook/d_cs_drugcode.pdf, pp. 13, accessed 23. January 2016
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