Profadol

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Not to be confused with Propanol, Propofol, or Propranolol.
Profadol
Profadol skeletal.svg
Systematic (IUPAC) name
3-(1-methyl-3-propyl-pyrrolidin-3-yl)phenol
Clinical data
Legal status
  • Schedule II (Analogue of Tapentadol) (US)
Identifiers
CAS Number 428-37-5
ATC code none
PubChem CID: 9882
ChemSpider 9498
UNII 41GDG43FTT YesY
ChEMBL CHEMBL161204
Chemical data
Formula C14H21NO
Molecular mass 219.32 g/mol

Profadol (CI-572) is an opioid analgesic which was developed in the 1960s by Parke-Davis.[1] It acts as a mixed agonist-antagonist of the μ-opioid receptor. The analgetic potency is about the same as of pethidine (meperidine), the antagonistic effect is 1/50 of Nalorphine.[2]

See also

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References

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  1. ↑ DE Patent 1303096
  2. ↑ Eberhard Schröder, Clemens Rufer, Ralph Schmiechen, Arzneimittelchemie I, Georg Thieme Verlag 1976 ISBN 3-13-520601-7
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