CD7
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). CD7 (Cluster of Differentiation 7) is a protein that in humans is encoded by the CD7 gene.[1]
Contents
Function
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.[1]
See also
Interactions
CD7 has been shown to interact with PIK3R1.[2][3]
Clinical significance
CD7 can be aberrantly expressed in refractory anaemia with excess blasts (RAEB) and may confer a worse prognosis.[4] Also, a lack of CD7 expression could insinuate mycosis fungoides (MF) or Sezary syndrome (SS).[5]
References
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External links
- CD7 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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