CD82 (gene)
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). CD82 (Cluster of Differentiation 82) is a human protein encoded by the CD82 gene.[1]
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[1]
Interactions
CD82 (gene) has been shown to interact with CD19,[2][3] CD63[4] and CD234[5]
See also
References
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External links
- CD82 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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