PHA-57378

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PHA-57378
240px
Systematic (IUPAC) name
2,7,8,9,10,11-hexahydro-1H-azepino[4,5-b][1,4]oxazino[2,3,4-hi]indole
Identifiers
CAS Number 303798-94-9 YesY
PubChem CID: 10198481
ChemSpider 8373981
Chemical data
Formula C14H16N2O
Molecular mass 228.29 g/mol
  • C1(OCC2)=C(N2C3=C4CCNCC3)C4=CC=C1
  • InChI=1S/C14H16N2O/c1-2-11-10-4-6-15-7-5-12(10)16-8-9-17-13(3-1)14(11)16/h1-3,15H,4-9H2
  • Key:KMVAXNRPZRSLSY-UHFFFAOYSA-N

PHA-57378 is a drug which acts as an agonist at serotonin 5-HT2 receptors,[1] having a binding affinity of 4.1 nM at the 5-HT2A subtype and 4.3 nM at 5-HT2C. It has anxiolytic effects in animal studies.[2]

See also

References

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  1. ↑ Jackson Hester et al. TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS. WIPO Patent Application WO 2000/064899, Priority date April 23, 1999
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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