SB-204741

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SB-204741
SB-204,741 structure.png
Systematic (IUPAC) name
N-(1-Methyl-1H-indol-5-yl)-N'-(3-methylisothiazol-5-yl)urea
Identifiers
CAS Number 152239-46-8 YesY
PubChem CID: 3277600
IUPHAR/BPS 221
Synonyms SB-204,741
Chemical data
Formula C14H14N4OS
Molecular mass 286.352 g/mol
  • c2c(C)nsc2NC(=O)Nc3ccc1n(C)ccc1c3
  (verify)

SB-204741 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 135x selectivity over the closely related 5-HT2C receptor, and even higher over the 5-HT2A receptor and other targets.[1] It is used in scientific research for investigating the functions of the 5-HT2B receptor.[2][3][4][5]

References

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