7,N,N-TMT

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7,N,N-TMT
7-TMT structure.png
Systematic (IUPAC) name
2-(7-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
Identifiers
CAS Number 65882-39-5 N
PubChem CID: 47747
ChemSpider 43445 YesY
ChEMBL CHEMBL20167 YesY
Chemical data
Formula C13H18N2
Molecular mass 202.30 g·mol−1
  • CC1=C(NC=C2CCN(C)C)C2=CC=C1
  • InChI=1S/C13H18N2/c1-10-5-4-6-12-11(7-8-15(2)3)9-14-13(10)12/h4-6,9,14H,7-8H2,1-3H3 YesY
  • Key:PQSFTUCFMWBITK-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

7,N,N-Trimethyltryptamine (7-methyl-DMT, 7-TMT), is a tryptamine derivative which acts as an agonist of 5-HT2 receptors.[1][2][3] In animal tests, both 7-TMT and its 5-methoxy derivative 5-MeO-7-TMT produced behavioural responses similar to those of psychedelic drugs such as DMT, but the larger 7-ethyl and 7-bromo derivatives of DMT did not produce psychedelic responses despite having higher 5-HT2 receptor affinity in vitro (cf. DOBU, DOAM).[4] 7-TMT also weakly inhibits reuptake of serotonin but with little effect on dopamine or noradrenaline reuptake.[5]

See also

References

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