AFDX-384

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AFDX-384
AFDX-384.svg
Systematic (IUPAC) name
N-(2-[(2R)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl)-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
Identifiers
CAS Number 118290-27-0 YesY
PubChem CID: 119357
ChemSpider 26233613 YesY
ChEBI CHEBI:73338 N
Chemical data
Formula C27H38N6O2
Molecular mass 478.628 g/mol
  • O=C1Nc2cccnc2N(c4c1cccc4)C(=O)NCCN3CCCCC3CN(CCC)CCC
  • InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)/t21-/m1/s1 YesY
  • Key:MZDYABXXPZNUCT-OAQYLSRUSA-N YesY
 NYesY (what is this?)  (verify)

AFDX-384 (BIBN-161) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes. It is used mainly for mapping the distribution of M2 and M4 muscarinic receptors in the brain, and studying their involvement in the development and treatment of dementia and schizophrenia.[1][2][3][4][5][6][7]

See also

References

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