Ipidacrine
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File:Ipidacrine.svg | |
Systematic (IUPAC) name | |
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2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine
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Clinical data | |
Trade names | Neiromidin |
Legal status |
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Identifiers | |
ATC code | N06DA05 (WHO) |
PubChem | CID: 604519 |
ChemSpider | 525510 |
ChEMBL | CHEMBL130880 |
Synonyms | Amiridine; NIK-247 |
Chemical data | |
Formula | C12H16N2 |
Molecular mass | 188.27 g/mol |
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Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation. This compound is a derivative of 4-aminopyridine and is structurally similar to tacrine.[1]
Ipidacrine is a reversible acetylcholinesterase inhibitor used in memory disorders of different origins.[2][3][4]
Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.[5]
References
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- Acetylcholinesterase inhibitors
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