Bacopa monnieri
Bacopa monnieri | |
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B. monnieri
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Binomial name | |
Bacopa monnieri |
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Bacopa monniera |
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Bacopa monnieri (waterhyssop, brahmi,[2] thyme-leafed gratiola, water hyssop, herb of grace,[2] Indian pennywort[2]) is a perennial, creeping herb native to the wetlands of southern India, Australia, Europe, Africa, Asia, and North and South America.[2] Bacopa is a medicinal herb used in Ayurveda, where it is also known as "Brahmi," after Brahmā, the creator God of the Hindu pantheon.
Contents
Description

The leaves of this plant are succulent, oblong and 4–6 mm (0.16–0.24 in) thick. Leaves are oblanceolate and are arranged oppositely on the stem. The flowers are small and white, with four to five petals. Its ability to grow in water makes it a popular aquarium plant. It can even grow in slightly brackish conditions. Propagation is often achieved through cuttings.[3]
Ecology
It commonly grows in marshy areas throughout India, Nepal, Sri Lanka, China, Pakistan, Taiwan, and Vietnam. It is also found in Florida, Hawaii and other southern states of the United States where it can be grown in damp conditions by a pond or bog garden.[4] This plant can be grown hydroponically.
Traditional uses
Bacopa has been used in traditional Ayurvedic treatment for epilepsy and asthma.[5] It is also used in Ayurveda for ulcers, tumors, ascites, enlarged spleen, inflammations, leprosy, anemia, and gastroenteritis.[3]
Nomenclature
Brahmi is also the name given to Centella asiatica, particularly in North India, and Kerala where it is also identified in Malayalam as muttil (മുത്തിള്) or kodakan. This identification of brāhmī as C. asiatica has been in use for long in northern India, as Hēmādri's Commentary on Aṣṭāṅgahṛdayaṃ (Āyuṛvēdarasāyanaṃ) treats maṇḍūkapaṛṇī (C. asiatica) as a synonym of brahmi,[6][7] although that may be a case of mistaken identification that was introduced during the 16th century.[8]
Bacopa monnieri was initially described around the 6th century A.D. in texts such as the Charaka Samhita, Atharva-Veda, and Susrut Samhita as a medhya rasayana–class herb taken to sharpen intellect and attenuate mental deficits. The herb was allegedly used by ancient Vedic scholars to memorize lengthy sacred hymns and scriptures.
Chemical constituents
The best characterized compounds in Bacopa monnieri are dammarane-type triterpenoid saponins known as bacosides, with jujubogenin or pseudo-jujubogenin moieties as aglycone units.[9] Bacosides comprise a family of 12 known analogs.[10] Other saponins called bacopasides I–XII have been identified more recently.[11] The alkaloids brahmine, nicotine, and herpestine have been catalogued, along with D-mannitol, apigenin, hersaponin, monnierasides I–III, cucurbitacin and plantainoside B.[12][13][14]
The constituent most studied has been bacoside A, which was found to be a blend of bacoside A3, bacopacide II, bacopasaponin C, and a jujubogenin isomer of bacosaponin C.[15] These assays have been conducted using whole plant extract, and bacoside concentrations may vary depending upon the part from which they are extracted. In one Bacopa monnieri sample, Rastogi et al. found this bacoside profile—bacopaside I (5.37%), bacoside A3 (5.59%), bacopaside II (6.9%), bacopasaponin C isomer (7.08%), and bacopasaponin C (4.18%).[16]
Research
Bacopa monnieri displays in vitro antioxidant and cell-protective effects.[17] In animals, it also inhibits acetylcholinesterase, activates choline acetyltransferase, and increases cerebral blood flow.[18]
Several studies have suggested that Bacopa monnieri extracts may have protective effects in animal models of neurodegeneration.[19] Small clinical trials in humans have found limited evidence supporting improved free memory recall, with no evidence supporting other cognition-enhancing effects.[20][21]
Toxicology
Aqueous extracts of Bacopa monnieri may have reversible adverse effects on spermatogenesis, sperm count, and fertility in male mice.[22]
The most commonly reported adverse side effects of Bacopa monnieri in humans are nausea, increased intestinal motility, and gastrointestinal upset.[23][24][non-primary source needed]
International naming
The plant is known by many names in many international languages, including:
- ബ്രഹ്മി in Malayalam (Kerala)
- ("Brahmi") Hindi (India)
- (Niirpirami)/ Valaarai in Tamil
- (Timare) in Kannada
- (Phak mi), พรมมิ (Phrommi) in Thai
- Lunuwila in Sinhalese (Sri Lanka)
- ʻaeʻae in Hawaiian (Hawaii)
- Rau Đắng in Vietnamese
- פְּשֵטָה שרועה ("psheta sru'a") in Hebrew
- Kleines Fettblatt in German
- 假马齿苋 ("Jiǎ mǎ chǐ xiàn") in Simplified Chinese
See also
- Withania somnifera (ashwagandha)
References
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Further reading
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External links
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Wikimedia Commons has media related to Bacopa monnieri. |
- USDA Plants Profile for Bacopa monnieri (herb of grace)
- Dr. Duke's Databases: Bacopa monnieri, list of chemicals
- Hort.Purdue.edu: Bacopa monnieri — by Pankaj Oudhia.
- Pharmasave: Bacopa — includes a number of medical references.
- ,Amrutaherbals.com; Bacopa Monograph — by Dr Ajay Padmawar.
- UC Photos gallery — Bacopa monnieri
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- ↑ Bhandari P, Kumar N, Singh B, Kaul VK. Cucurbitacins from Bacopa monnieri. Phytochemistry 2007.
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- Pages with reference errors
- Wikipedia articles needing factual verification from February 2013
- Wikipedia articles needing factual verification from January 2014
- Commons category link is defined as the pagename
- Plantaginaceae
- Brackish water plants
- Freshwater plants
- Flora of Africa
- Flora of the Caribbean
- Flora of North America
- Flora of Oceania
- Flora of South America
- Flora of temperate Asia
- Flora of Indo-China
- Flora of the Indian Subcontinent
- Flora of Malesia
- Flora of the Southeastern United States
- Medicinal plants of Asia
- Medicinal plants of North America
- Medicinal plants of Oceania
- Medicinal plants of South America
- Plants used in Ayurveda